Application of FLP-FRT System to Construct Unmarked Deletion in Helicobacter pylori and Functional Study of Gene hp0788 in Pathogenesis

Application of FLP-FRT System to Construct Unmarked Deletion in Helicobacter pylori and Functional Study of Gene hp0788 in Pathogenesis

Helicobacter pylori is a Gram-negative, microaerophilic bacterium associated with human gastric diseases. Further investigations on virulence genes are still required to clarify the pathogenic mechanism of H. pylori and the heterogeneous problem of infection. In order to develop an efficient and acc...

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Bibliographic Details
Main Authors: Xiaofei Ji, Ying Wang, Jiaojiao Li, Qianyu Rong, Xingxing Chen, Ying Zhang, Xiaoning Liu, Boqing Li, Huilin Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Helicobacter pylori
unmarked deletion
FLP-FRT
hp0788
cell apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02357/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02357/full

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