Role of ferroptosis in radiation-induced soft tissue injury

Abstract Ionizing radiation has been pivotal in cancer therapy since its discovery. Despite its therapeutic benefits, IR causes significant acute and chronic complications due to DNA damage and the generation of reactive oxygen species, which harm nucleic acids, lipids, and proteins. While cancer ce...

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Bibliographic Details
Main Authors: Charlotte E. Berry, Carter B. Kendig, Nicholas An, Alexander Z. Fazilat, Andrew A. Churukian, Michelle Griffin, Phoebe M. Pan, Michael T. Longaker, Scott J. Dixon, Derrick C. Wan
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02003-5