Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis

Transient receptor potential vanilloid 4 (TRPV4) has been implicated in many disease conditions also in the lung. Its activation leads to an increase endothelial permeability in an intracellular calcium-influx dependent manner. We investigated its function in vitro on primary human endothelial cells...

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Bibliographic Details
Main Authors: N. Pairet, S. Mang, T. Kiechle, N. Laufhäger, P. Dietl, D.J. Lamb
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818302012