Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis
Transient receptor potential vanilloid 4 (TRPV4) has been implicated in many disease conditions also in the lung. Its activation leads to an increase endothelial permeability in an intracellular calcium-influx dependent manner. We investigated its function in vitro on primary human endothelial cells...
Main Authors: | N. Pairet, S. Mang, T. Kiechle, N. Laufhäger, P. Dietl, D.J. Lamb |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Biochemistry and Biophysics Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580818302012 |
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