Beneficial Effects of Tacrolimus on Brain-Death-Associated Right Ventricular Dysfunction in Pigs

Beneficial Effects of Tacrolimus on Brain-Death-Associated Right Ventricular Dysfunction in Pigs

Background: Right ventricular (RV) dysfunction remains a major problem after heart transplantation and may be associated with brain death (BD) in a donor. A calcineurin inhibitor tacrolimus was recently found to have beneficial effects on heart function. Here, we examined whether tacrolimus might pr...

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Bibliographic Details
Main Authors: Asmae Belhaj, Laurence Dewachter, Astrid Monier, Gregory Vegh, Sandrine Rorive, Myriam Remmelink, Mélanie Closset, Christian Melot, Jacques Creteur, Isabelle Salmon, Benoît Rondelet
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
heart transplantation
right ventricular dysfunction
brain death
FK506
tacrolimus
calcineurin inhibitor
Online Access:https://www.mdpi.com/1422-0067/24/13/10439

Internet

https://www.mdpi.com/1422-0067/24/13/10439

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