Comprehensive Analysis of Adverse Events Induced by PARP Inhibitors Using JADER and Time to Onset

Comprehensive Analysis of Adverse Events Induced by PARP Inhibitors Using JADER and Time to Onset

Poly (ADP-ribose) polymerase (PARP) inhibitors are effective against breast cancer susceptibility gene (<i>BRCA</i>) mutations. Clinical trials have reported hematologic toxicity and gastrointestinal symptoms as class effects of PARP inhibitors. However, information on adverse events (AE...

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Bibliographic Details
Main Authors: Kenta Yamaoka, Masaki Fujiwara, Mayako Uchida, Yoshihiro Uesawa, Nobuyuki Muroi, Tadashi Shimizu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Life
Subjects:
Poly (ADP-ribose) polymerase (PARP) inhibitor
olaparib
niraparib
spontaneous reporting system
Japanese Adverse Drug Event Reporting (JADER)
pharmacovigilance
Online Access:https://www.mdpi.com/2075-1729/12/9/1355

Internet

https://www.mdpi.com/2075-1729/12/9/1355

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