A Review of P-Glycoprotein Function and Regulation in Fish

The teleost ATP Binding Cassette (ABC) transporter P-glycoprotein (P-gp) is an active transmembrane transporter that plays a pivotal role in facilitating the movement of both endogenous and xenobiotic substrates (moderately hydrophobic and amphipathic compounds) across cell membranes. P-gp exhibits...

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Bibliographic Details
Main Authors: Christina U. Johnston, Christopher J. Kennedy
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Fishes
Subjects:
Online Access:https://www.mdpi.com/2410-3888/9/2/51