Oxidative stress induces mitochondrial iron overload and ferroptotic cell death

Abstract Oxidative stress has been shown to induce cell death in a wide range of human diseases including cardiac ischemia/reperfusion injury, drug induced cardiotoxicity, and heart failure. However, the mechanism of cell death induced by oxidative stress remains incompletely understood. Here we pro...

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Bibliographic Details
Main Authors: Yi Chen, Xiaoyun Guo, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Sulail Fatima, Qinghang Liu
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42760-4