Differentiation of endogenous erythropoietin and exogenous ESAs by Western blotting

Differentiation of endogenous erythropoietin and exogenous ESAs by Western blotting

Doping tests for the illegal use of erythropoiesis-stimulating agents (ESAs) have been developed. We developed a new Western blotting method to detect and distinguish endogenous erythropoietin (Epo, 35-38 kDa) and exogenous ESAs (epoetin α and β, 38-42 kDa; darbepoetin α, 47-50 kDa; epoetin β pegol,...

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Bibliographic Details
Main Authors: Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Tetsuro Yamashita, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Yuichi Sato, Jeff M. Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Heliyon
Subjects:
Biotechnology
Biochemistry
Molecular biology
Public health
Hematological system
Renal system
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020322325

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http://www.sciencedirect.com/science/article/pii/S2405844020322325

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