DUX: One Transcription Factor Controls 2-Cell-like Fate

DUX: One Transcription Factor Controls 2-Cell-like Fate

The double homeobox <i>(Dux</i>) gene, encoding a double homeobox transcription factor, is one of the key drivers of totipotency in mice. Recent studies showed Dux was temporally expressed at the 2-cell stage and acted as a transcriptional activator during zygotic genome activation (ZGA)...

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Bibliographic Details
Main Authors: Wei Ren, Leilei Gao, Yaling Mou, Wen Deng, Jinlian Hua, Fan Yang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
2-cell-like cells
Dux
gene regulation
totipotency
Online Access:https://www.mdpi.com/1422-0067/23/4/2067

Internet

https://www.mdpi.com/1422-0067/23/4/2067

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