Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice

Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice

BackgroundAlthough activation of inflammatory processes is essential to fight infections, its prolonged impact on brain function is well known to contribute to the pathophysiology of many medical conditions, including neuropsychiatric disorders. Therefore, identifying novel strategies to selectively...

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Bibliographic Details
Main Authors: Camille Monchaux de Oliveira, Jennifer Morael, Alexandrine Guille, Camille Amadieu, Sylvie Vancassel, David Gaudout, Lucile Capuron, Line Pourtau, Nathalie Castanon
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Nutrition
Subjects:
nutritional interventions
saffron extract
neuroinflammation
lipopolysaccharide
sickness behavior
kynurenine pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1267839/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2023.1267839/full

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