Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART

Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART

Summary: HIV persists in tissues during antiretroviral therapy (ART), but the relative contribution of different anatomical compartments to the viral reservoir in humans remains unknown. We performed an extensive characterization of HIV reservoirs in two men who donated their bodies to HIV cure rese...

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Bibliographic Details
Main Authors: Caroline Dufour, Maria Julia Ruiz, Amélie Pagliuzza, Corentin Richard, Aniqa Shahid, Rémi Fromentin, Rosalie Ponte, Amélie Cattin, Tomas Raul Wiche Salinas, Syim Salahuddin, Teslin Sandstrom, Stephanie Burke Schinkel, Cecilia T. Costiniuk, Mohammad-Ali Jenabian, Petronela Ancuta, Jean-Pierre Routy, Éric A. Cohen, Zabrina L. Brumme, Christopher Power, Jonathan B. Angel, Nicolas Chomont
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010641

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http://www.sciencedirect.com/science/article/pii/S2211124723010641

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