Increased bacterial taxonomic and functional diversity is associated with impaired rotavirus vaccine immunogenicity in infants from India and Malawi

Increased bacterial taxonomic and functional diversity is associated with impaired rotavirus vaccine immunogenicity in infants from India and Malawi

Abstract The immunogenicity and effectiveness of oral rotavirus vaccines (ORVs) against severe rotavirus-associated gastroenteritis are impaired in low- and middle-income countries (LMICs) where the burden of disease is highest. Determining risk factors for impaired ORV response may help identify st...

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Bibliographic Details
Main Authors: Edward Cunningham-Oakes, Christina Bronowski, End Chinyama, Khuzwayo C. Jere, Kulandaipalayam Natarajan C. Sindhu, Gagandeep Kang, Miren Iturriza-Gómara, Alistair C. Darby, Edward P. K. Parker
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Microbiology
Subjects:
Immunogenicity
Metagenomics
Microbiome
Rotavirus
Vaccine
Online Access:https://doi.org/10.1186/s12866-023-03098-z

Internet

https://doi.org/10.1186/s12866-023-03098-z

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