A novel BRCA2 splice variant identified in a young woman

A novel BRCA2 splice variant identified in a young woman

Abstract Background BRCA1/2 VUSs represent an important clinical issue in risk assessment for the breast/ovarian cancer families (HBOC) families. Among them, some occurring within the intron‐exon boundary may lead to aberrant splicing process by altering or creating de novo splicing regulatory eleme...

Full description

Bibliographic Details
Main Authors: Arianna Nicolussi, Francesca Belardinilli, Laura Ottini, Marialaura Petroni, Carlo Capalbo, Giuseppe Giannini, Anna Coppa
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
BRCA2
hereditary breast/ovarian cancer
splice variant
VUS
Online Access:https://doi.org/10.1002/mgg3.1513

Internet

https://doi.org/10.1002/mgg3.1513

Similar Items