Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS

Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS

This study aimed to evaluate if the treatment with metformin affects the morphologic structure, endothelial function, angiogenesis, inflammation and oxidation-responsive pathways in the heart of mice with surgically induced endometriosis. B6CBA/F1 mice (n = 37) were divided into four groups; Sham (S...

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Bibliographic Details
Main Authors: Ana Filipa Martins, Ana Catarina Neto, Adriana Raquel Rodrigues, Sandra Marisa Oliveira, Cláudia Sousa-Mendes, Adelino Leite-Moreira, Alexandra Maria Gouveia, Henrique Almeida, Delminda Neves
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
cardiac fibrosis
endometriosis
endothelial dysfunction
inflammation
metformin
Online Access:https://www.mdpi.com/2227-9059/10/11/2782

Internet

https://www.mdpi.com/2227-9059/10/11/2782

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