Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation

Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation

Abstract Background Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into chromatin. H3.3 is the ancestral H3 variant with k...

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Bibliographic Details
Main Authors: Syed Nabeel-Shah, Jyoti Garg, Kanwal Ashraf, Renu Jeyapala, Hyunmin Lee, Alexandra Petrova, James D. Burns, Shuye Pu, Zhaolei Zhang, Jack F. Greenblatt, Ronald E. Pearlman, Jean-Philippe Lambert, Jeffrey Fillingham
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Epigenetics & Chromatin
Subjects:
H3.3
Histone variant
HIRA
CAF1
Asf1
NASP
Online Access:https://doi.org/10.1186/s13072-023-00484-9

Internet

https://doi.org/10.1186/s13072-023-00484-9

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