Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function

Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function

Abstract Background Brain pericytes participate in the regulation of cerebral blood flow and the maintenance of blood–brain barrier integrity. Because of their perivascular localization, their receptor repertoire, and their potential ability to respond to inflammatory and infectious stimuli by produ...

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Bibliographic Details
Main Authors: Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Sven Hammerschmidt, Roland E. Kälin, Hans-Walter Pfister, Matthijs C. Brouwer, Matthias Klein, Rainer Glass, Diederik van de Beek, Uwe Koedel
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Neuroinflammation
Subjects:
Pericytes
Pneumococcal meningitis
Blood–brain barrier
Streptococcus pneumoniae
Online Access:https://doi.org/10.1186/s12974-023-02938-z

Internet

https://doi.org/10.1186/s12974-023-02938-z

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