Proton Pump Inhibitor-Induced Gut Dysbiosis Increases Mortality Rates for Patients with Clostridioides difficile Infection

Proton Pump Inhibitor-Induced Gut Dysbiosis Increases Mortality Rates for Patients with Clostridioides difficile Infection

ABSTRACT Clostridioides difficile infection (CDI) is associated with high mortality rates among patients with chronic illnesses. We aimed to identify avoidable risk factors to reduce the mortality rate in CDI patients. A total of 306 patients with diarrhea and clinical suspicion of CDI were enrolled...

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Bibliographic Details
Main Authors: Cheng-Yu Lin, Hao-Tsai Cheng, Chia-Jung Kuo, Yun-Shien Lee, Chang-Mu Sung, Micah Keidan, Krishna Rao, John Y. Kao, Sen-Yung Hsieh
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
CDI-associated gut dysbiosis
PPI-induced gut dysbiosis
gut microbiota
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00486-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00486-22

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