Multitargeting Histamine H<sub>3</sub> Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives

Multitargeting Histamine H<sub>3</sub> Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives

Alzheimer’s disease (AD) is a neurodegenerative disorder, for which there is no effective cure. Current drugs only slow down the course of the disease, and, therefore, there is an urgent need to find effective therapies that not only treat, but also prevent it. Acetylcholinesterase inhibitors (AChEI...

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Bibliographic Details
Main Authors: Dorota Łażewska, Maria Kaleta, Paula Zaręba, Justyna Godyń, Mariam Dubiel, Ewelina Honkisz-Orzechowska, Agata Doroz-Płonka, Anna Więckowska, Holger Stark, Katarzyna Kieć-Kononowicz
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
histamine H<sub>3</sub> receptor ligand
cholinesterase inhibitor
kinetic studies
toxicity
HepG2 lines
SH-SY5Y lines
Online Access:https://www.mdpi.com/1420-3049/28/5/2349

Internet

https://www.mdpi.com/1420-3049/28/5/2349

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