Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sjögren’s syndrome

Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sjögren’s syndrome

Abstract Background Patients with Sjögren’s syndrome, like other patients with autoimmune disorders, display dysregulation in the function of their immune system. Fas and Fas Ligand (FasL) are among the dysregulated proteins. Methods We studied Fas and FasL on IL-2Rα+ cells and in serum of patients...

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Bibliographic Details
Main Authors: Irena Lindrova, Martina Kolackova, Tereza Svadlakova, Radka Vankova, Marcela Chmelarova, Michaela Rosecka, Eva Jozifkova, Martin Sembera, Jan Krejsek, Radovan Slezak
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Immunology
Subjects:
Autoimmune disorders
Fas
Fas Ligand
CD95
CD95L
Sjögren’s syndrome
Online Access:https://doi.org/10.1186/s12865-023-00544-5

Internet

https://doi.org/10.1186/s12865-023-00544-5

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