An integrated regulatory network reveals pervasive cross-regulation among transcription and splicing factors.

Traditionally the gene expression pathway has been regarded as being comprised of independent steps, from RNA transcription to protein translation. To date there is increasing evidence of coupling between the different processes of the pathway, specifically between transcription and splicing. To stu...

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Bibliographic Details
Main Authors: Idit Kosti, Predrag Radivojac, Yael Mandel-Gutfreund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3405991?pdf=render