Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells.

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells.

In this study, we developed a methodology to improve the survival, vascular differentiation and regenerative potential of umbilical cord blood (UCB)-derived hematopoietic stem cells (CD34(+) cells), by co-culturing the stem cells in a 3D fibrin gel with CD34(+)-derived endothelial cells (ECs). ECs d...

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Bibliographic Details
Main Authors: Dora C S Pedroso, Ana Tellechea, Liane Moura, Isabel Fidalgo-Carvalho, João Duarte, Eugénia Carvalho, Lino Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3026015?pdf=render

Internet

http://europepmc.org/articles/PMC3026015?pdf=render

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