Bcl-2 homologue Debcl enhances α-synuclein-induced phenotypes in Drosophila

Background Parkinson disease (PD) is a debilitating movement disorder that afflicts 1–2% of the population over 50 years of age. The common hallmark for both sporadic and familial forms of PD is mitochondrial dysfunction. Mammals have at least twenty proapoptotic and antiapoptotic Bcl-2 family membe...

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Bibliographic Details
Main Authors: P. Githure M’Angale, Brian E. Staveley
Format: Article
Language:English
Published: PeerJ Inc. 2016-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2461.pdf