Sex-specific hypothalamic neuropathology and glucose metabolism in an amyloidosis transgenic mouse model of Alzheimer’s disease

Sex-specific hypothalamic neuropathology and glucose metabolism in an amyloidosis transgenic mouse model of Alzheimer’s disease

Abstract Background Amyloid toxicity and glucose metabolic disorders are key pathological features during the progression of Alzheimer’s disease (AD). While the hypothalamus plays a crucial role in regulating systemic energy balance, the distribution of amyloid plaques in the preoptic, anterior, tub...

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Bibliographic Details
Main Authors: Guibo Qi, Han Tang, Pifang Gong, Yitong Liu, Chenzhao He, Jianian Hu, Siying Kang, Liang Chen, Song Qin
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Cell & Bioscience
Subjects:
Alzheimer’s disease
Amyloid plaque
Glucose metabolism
Gliosis
Hypothalamus
Neuropathology
Online Access:https://doi.org/10.1186/s13578-024-01295-5

Internet

https://doi.org/10.1186/s13578-024-01295-5

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