Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 35

Oncolytic adenoviruses (OAds) are among the most promising oncolytic viruses. Almost all oncolytic adenoviruses are composed of human adenovirus serotype 5 (Ad5) (OAd5). However, expression of the primary infection receptor for Ad5, coxsackievirus-adenovirus receptor (CAR), often declines on maligna...

Full description

Bibliographic Details
Main Authors: Ryosuke Ono, Kosuke Takayama, Fuminori Sakurai, Hiroyuki Mizuguchi
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521000164