Sodium Malonate Inhibits the AcrAB-TolC Multidrug Efflux Pump of <i>Escherichia coli</i> and Increases Antibiotic Efficacy

There is an urgent need to find novel treatments for combating multidrug-resistant bacteria. Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this problem. Therefore, using efflux pump inhibitors (EPIs) is a promising strategy to increase antibiotic efficacy. Howe...

Full description

Bibliographic Details
Main Authors: Allea Cauilan, Cristian Ruiz
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/12/1409