Sodium Malonate Inhibits the AcrAB-TolC Multidrug Efflux Pump of <i>Escherichia coli</i> and Increases Antibiotic Efficacy
There is an urgent need to find novel treatments for combating multidrug-resistant bacteria. Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this problem. Therefore, using efflux pump inhibitors (EPIs) is a promising strategy to increase antibiotic efficacy. Howe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/11/12/1409 |