Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry

Abstract Masitinib (MST) is an orally administered drug that targets mast cells and macrophages, important cells for immunity, by inhibiting a limited number of tyrosine kinases. It is currently registered in Europe and USA for the treatment of mast cell tumors in dogs. AB Science announced that the...

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Bibliographic Details
Main Authors: Adnan A. Kadi, Sawsan M. Amer, Hany W. Darwish, Mohamed W. Attwa
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Chemistry Central Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13065-018-0429-y