Repurposed drug molecules targeting NSP12 protein of SARS-CoV-2: An in-silico study

Repurposed drug molecules targeting NSP12 protein of SARS-CoV-2: An in-silico study

The emergence of SARS-CoV-2 created a havoc worldwide, causing high morbidity, serious complications and mortality. The ORF1ab of SARS-CoV-2 has 16 non-structural proteins which are required for genome replication and transcription. All of these are druggable targets, of which NSP12 (RNA-dependent R...

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Bibliographic Details
Main Authors: Bhawna Sharma, Bennet Angel, Vankadoth Umakanth Naik, Annette Angel, Vinod Joshi, BM Shareef, Neha Singh, Ambreen Shafaat Khan, Poorna Khaneja, Shilpa Barthwal, Ramesh Joshi, Nuzhat Maqbool Peer, Kiran Yadav, Komal Tomar, Satendra Pal Singh
Format: Article
Language:English
Published: AIMS Press 2023-12-01
Series:AIMS Molecular Science
Subjects:
sars-cov-2
remdesivir
rdrp
respiratory drugs
docking
md simulation
Online Access:https://www.aimspress.com/article/doi/10.3934/molsci.2023019?viewType=HTML

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https://www.aimspress.com/article/doi/10.3934/molsci.2023019?viewType=HTML

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