Mechanical Deformation Mechanisms and Properties of Prion Fibrils Probed by Atomistic Simulations

Mechanical Deformation Mechanisms and Properties of Prion Fibrils Probed by Atomistic Simulations

Abstract Prion fibrils, which are a hallmark for neurodegenerative diseases, have recently been found to exhibit the structural diversity that governs disease pathology. Despite our recent finding concerning the role of the disease-specific structure of prion fibrils in determining their elastic pro...

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Bibliographic Details
Main Authors: Bumjoon Choi, Taehee Kim, Eue Soo Ahn, Sang Woo Lee, Kilho Eom
Format: Article
Language:English
Published: SpringerOpen 2017-03-01
Series:Nanoscale Research Letters
Subjects:
Prion fibril
Mechanical deformation mechanism
Fracture property
Atomistic simulation
Online Access:http://link.springer.com/article/10.1186/s11671-017-1966-3

Internet

http://link.springer.com/article/10.1186/s11671-017-1966-3

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