Fast, scalable, Bayesian spike identification for multi-electrode arrays.

We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes overlap, and accounts for intrinsic variability of spikes from each unit. As MEAs grow larger, it i...

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Bibliographic Details
Main Authors: Jason S Prentice, Jan Homann, Kristina D Simmons, Gašper Tkačik, Vijay Balasubramanian, Philip C Nelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3140468?pdf=render