MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men

MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men

The role of mitochondrial ROS in signalling muscle adaptations to exercise training has not been explored in detail. We investigated the effect of supplementation with the mitochondria-targeted antioxidant MitoQ on a) the skeletal muscle mitochondrial and antioxidant gene transcriptional response to...

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Bibliographic Details
Main Authors: S.C. Broome, T. Pham, A.J. Braakhuis, R. Narang, H.W. Wang, A.J.R. Hickey, C.J. Mitchell, T.L. Merry
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Subjects:
Mitochondria
Antioxidant
Exercise
ROS
Adaptation
Performance
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001136

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http://www.sciencedirect.com/science/article/pii/S2213231722001136

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