Bone marrow-derived neural crest precursors improve nerve defect repair partially through secreted trophic factors

Bone marrow-derived neural crest precursors improve nerve defect repair partially through secreted trophic factors

Abstract Background Emerging evidence suggests that neural crest-derived cells (NCCs) present important functions in peripheral nerve regeneration to correct the insufficiency of autogenous Schwann cells. Postmigratory NCCs have been successfully isolated from adult rat bone marrow in our previous w...

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Bibliographic Details
Main Authors: Haiyan Shi, Xiaoli Li, Junling Yang, Yahong Zhao, Chengbin Xue, Yaxian Wang, Qianru He, Mi Shen, Qi Zhang, Yumin Yang, Fei Ding
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
Neural crest
Precursor
Schwann cell
Nerve regeneration
Trophic factor
Bone marrow
Online Access:https://doi.org/10.1186/s13287-019-1517-1

Internet

https://doi.org/10.1186/s13287-019-1517-1

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