Bladder Cancer Exhibiting High Immune Infiltration Shows the Lowest Response Rate to Immune Checkpoint Inhibitors

Bladder Cancer Exhibiting High Immune Infiltration Shows the Lowest Response Rate to Immune Checkpoint Inhibitors

Background: Bladder urothelial cancer (BLCA) treatment using immune checkpoint inhibitors (IMCIs) can result in long-lasting clinical benefits. However, only a fraction of patients respond to such treatment. In this study, we aimed to identify the relationships between immune cell infiltration level...

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Bibliographic Details
Main Authors: Shen Pan, Yunhong Zhan, Xiaonan Chen, Bin Wu, Bitian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
bladder urothelial cancer
molecular subtype
single-sample gene set enrichment analysis
weighted gene co-expression network analysis
immune checkpoint inhibitor
immune cell infiltration level
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01101/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01101/full

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