Exploring <i>Proteus mirabilis</i> Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

Currently, the treatment of <i>Proteus mirabilis</i> infections is considered to be complicated as the organism has become resistant to numerous antibiotic classes. Therefore, new inhibitors should be developed, targeting bacterial molecular functions. Methionine tRNA synthetase (MetRS),...

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Bibliographic Details
Main Authors: Samar S. Elbaramawi, Ahmed G. Eissa, Nada A. Noureldin, Claire Simons
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/9/1263