Exploring <i>Proteus mirabilis</i> Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

Exploring <i>Proteus mirabilis</i> Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

Currently, the treatment of <i>Proteus mirabilis</i> infections is considered to be complicated as the organism has become resistant to numerous antibiotic classes. Therefore, new inhibitors should be developed, targeting bacterial molecular functions. Methionine tRNA synthetase (MetRS),...

Full description

Bibliographic Details
Main Authors: Samar S. Elbaramawi, Ahmed G. Eissa, Nada A. Noureldin, Claire Simons
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
<i>Proteus mirabilis</i>
homology model
methionyl tRNA synthetase
virtual screening
urinary tract infections
molecular dynamics
Online Access:https://www.mdpi.com/1424-8247/16/9/1263

Internet

https://www.mdpi.com/1424-8247/16/9/1263

Similar Items