1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione

1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione

A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification. Therefore, the proposed method, with an overall yield of 60%, offers a fac...

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Bibliographic Details
Main Authors: Vasiliki Pardali, Sotirios Katsamakas, Erofili Giannakopoulou, Grigoris Zoidis
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molbank
Subjects:
carbocyclic hydantoins
N-1 substituted hydantoin
spiro hydantoins
imidazolidine-2,4-diones
DFT calculations
stereochemistry
Online Access:https://www.mdpi.com/1422-8599/2021/2/M1228

Internet

https://www.mdpi.com/1422-8599/2021/2/M1228

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