Phenotypic and functional evaluation of CD3+CD4−CD8− T cells in human CD8 immunodeficiency

Background Human CD8 immunodeficiency is characterized by undetectable CD8+ lymphocytes and an increased population of CD4−CD8− (double negative) T lymphocytes.Design and Methods We hypothesized that the double negative subset corresponds to the cellular population that should express CD8 and is com...

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Bibliographic Details
Main Authors: Iván Bernardo, Esther Mancebo, Ignacio Aguiló, Alberto Anel, Luis M. Allende, Juan M. Guerra-Vales, Jesús Ruiz–Contreras, Antonio Serrano, Paloma Talayero, Oscar de la Calle, Cecilia Gonzalez-Santesteban, Estela Paz-Artal
Format: Article
Language:English
Published: Ferrata Storti Foundation 2011-08-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6047