Design choices for observational studies of the effect of exposure on disease incidence

The purpose of this paper is to help readers choose an appropriate observational study design for measuring an association between an exposure and disease incidence. We discuss cohort studies, sub-samples from cohorts (case-cohort and nested case-control designs), and population-based or hospital-ba...

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Bibliographic Details
Main Authors: Douglas G Altman, Mark Woodward, Mitchell H Gail, Gary Collins, Suzanne M Cadarette, Stephen JW Evans, Peggy Sekula, Elizabeth Williamson
Format: Article
Language:English
Published: BMJ Publishing Group 2019-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/12/e031031.full