Macrophages mediate psoriasis via Mincle-dependent mechanism in mice

Abstract Psoriasis is currently considered to be an immune and inflammatory disease characterized by massive immune cells infiltration including macrophages. It has been reported that macrophage-inducible C-type lectin (Mincle) is essential to maintain the pro-inflammatory phenotype of M1 macrophage...

Full description

Bibliographic Details
Main Authors: Rui-zhi Tan, Xia Zhong, Rang-yue Han, Ke-huan Xie, Jian Jia, Ye Yang, Mei Cheng, Chun-yan Yang, Hui-yao Lan, Li Wang
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01444-8