RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype

RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype

Bone metastatic cancer-secreted extracellular factors are capable of modifying the bone microenvironment through interacting with bone cells, including osteoblasts. Reticulum ribosome-binding protein 1 (RRBP1) is substantially expressed in certain bone metastatic cancer cells. This study was underta...

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Bibliographic Details
Main Authors: Rui Chen, Yue Wang, Yang Xu, Yaohui He, Qing Li, Chun Xia, Bing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
RRBP1
conditioned mediums (CMs)
bone metastatic cancer cells
the osteoblastic phenotype expression
MC3T3-E1 cells
endoplasmic reticulum (ER) stress
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1005152/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1005152/full

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