Osmostress-induced cell volume loss delays yeast Hog1 signaling by limiting diffusion processes and by Hog1-specific effects.

Signal transmission progresses via a series of transient protein-protein interactions and protein movements, which require diffusion within a cell packed with different molecules. Yeast Hog1, the effector protein kinase of the High Osmolarity Glycerol pathway, translocates transiently from the cytos...

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Bibliographic Details
Main Authors: Roja Babazadeh, Caroline Beck Adiels, Maria Smedh, Elzbieta Petelenz-Kurdziel, Mattias Goksör, Stefan Hohmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3835318?pdf=render