Overview of Trop-2 in Cancer: From Pre-Clinical Studies to Future Directions in Clinical Settings

Overview of Trop-2 in Cancer: From Pre-Clinical Studies to Future Directions in Clinical Settings

Trophoblast cell surface antigen-2 (Trop-2) is a glycoprotein that was first described as a membrane marker of trophoblast cells and was associated with regenerative abilities. Trop-2 overexpression was also described in several tumour types. Nevertheless, the therapeutic potential of Trop-2 was wid...

Full description

Bibliographic Details
Main Authors: Pasquale Lombardi, Marco Filetti, Rosa Falcone, Valeria Altamura, Francesco Paroni Sterbini, Emilio Bria, Alessandra Fabi, Diana Giannarelli, Giovanni Scambia, Gennaro Daniele
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
Trop-2
ADC
target therapy
bystander effect
Online Access:https://www.mdpi.com/2072-6694/15/6/1744

Internet

https://www.mdpi.com/2072-6694/15/6/1744

Similar Items