Intra- and inter-operator variability in MRI-based manual segmentation of HCC lesions and its impact on dosimetry

Intra- and inter-operator variability in MRI-based manual segmentation of HCC lesions and its impact on dosimetry

Abstract Purpose The aim was to quantify inter- and intra-observer variability in manually delineated hepatocellular carcinoma (HCC) lesion contours and the resulting impact on radioembolization (RE) dosimetry. Methods Ten patients with HCC lesions treated with Y-90 RE and imaged with post-therapy Y...

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Bibliographic Details
Main Authors: Elise C. Covert, Kellen Fitzpatrick, Justin Mikell, Ravi K. Kaza, John D. Millet, Daniel Barkmeier, Joseph Gemmete, Jared Christensen, Matthew J. Schipper, Yuni K. Dewaraja
Format: Article
Language:English
Published: SpringerOpen 2022-12-01
Series:EJNMMI Physics
Subjects:
Uncertainty analysis
Dosimetry
Segmentation
Radioembolization
Observer studies
Radionuclide therapy
Online Access:https://doi.org/10.1186/s40658-022-00515-6

Internet

https://doi.org/10.1186/s40658-022-00515-6

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