Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis

Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis

Abstract The exact mechanisms and temporal sequence of neurodegeneration in multiple sclerosis are still unresolved. The visual pathway including its unmyelinated retinal axons, can serve as a prototypic model of neurodegeneration in experimental optic neuritis. We conducted a longitudinal study com...

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Bibliographic Details
Main Authors: Praveena Manogaran, Marijana Samardzija, Anaïs Nura Schad, Carla Andrea Wicki, Christine Walker-Egger, Markus Rudin, Christian Grimm, Sven Schippling
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Acta Neuropathologica Communications
Subjects:
Optical coherence tomography
Optic neuritis
Retina
Experimental autoimmune encephalomyelitis
Neuro-axonal degeneration
Gliosis
Online Access:http://link.springer.com/article/10.1186/s40478-019-0768-5

Internet

http://link.springer.com/article/10.1186/s40478-019-0768-5

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