Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720308715 |