Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice.

Cognitive dysfunction is one of the most common postoperative complications experienced by older patients after anesthesia and surgery but the cause remains unknown. Immune molecules are essential for many aspects of neural homeostasis, including learning and memory, and an imbalance in immune neuro...

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Bibliographic Details
Main Authors: Matthew B Friese, Miriam Nathan, Deborah J Culley, Gregory Crosby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209283