scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells

In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence similarity and the use of the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), with severe acute respiratory syndrome coronavi...

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Bibliographic Details
Main Authors: Zhengpin Wang, Xiaojiang Xu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/920