Diosmin mitigates dexamethasone-induced osteoporosis in vivo: Role of Runx2, RANKL/OPG, and oxidative stress

Diosmin mitigates dexamethasone-induced osteoporosis in vivo: Role of Runx2, RANKL/OPG, and oxidative stress

Secondary osteoporosis is commonly caused by long-term intake of glucocorticoids (GCs), such as dexamethasone (DEX). Diosmin, a natural substance with potent antioxidant and anti-inflammatory properties, is clinically used for treating some vascular disorders. The current work targeted exploring the...

Full description

Bibliographic Details
Main Authors: El-Shaimaa A. Arafa, Noran O. Elgendy, Mai A. Elhemely, Eglal A. Abdelaleem, Wafaa R. Mohamed
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Osteoporosis
Glucocorticoids
Diosmin
RANKL/OPG
Runx-2
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002494

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223002494

Similar Items