LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling
Abstract Background The abnormal expression of leucine-rich-alpha-2-glycoprotein 1 (LRG-1) is reported to be associated with multiple malignancies, but its role in the progression of pancreatic ductal adenocarcinoma (PDAC) remains to be determined. Methods The expression of LRG-1 was assessed in PDA...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-019-1088-0 |