Neutralizing mAbs against SFTS Virus Gn Protein Show Strong Therapeutic Effects in an SFTS Animal Model

Neutralizing mAbs against SFTS Virus Gn Protein Show Strong Therapeutic Effects in an SFTS Animal Model

Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease with a high case fatality rate caused by the SFTS virus, and currently there are no approved specific treatments. Neutralizing monoclonal antibodies (mAbs) against the virus could be a therapeutic agent in SFTS treatment, bu...

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Bibliographic Details
Main Authors: Masayuki Shimojima, Satoko Sugimoto, Kunihiko Umekita, Taishi Onodera, Kaori Sano, Hideki Tani, Yuki Takamatsu, Tomoki Yoshikawa, Takeshi Kurosu, Tadaki Suzuki, Yoshimasa Takahashi, Hideki Ebihara, Masayuki Saijo
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
severe fever with thrombocytopenia syndrome (SFTS)
SFTS virus
therapeutic monoclonal antibody
neutralization
animal model
Online Access:https://www.mdpi.com/1999-4915/14/8/1665

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https://www.mdpi.com/1999-4915/14/8/1665

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