Potential use of clinical polygenic risk scores in psychiatry – ethical implications and communicating high polygenic risk

Potential use of clinical polygenic risk scores in psychiatry – ethical implications and communicating high polygenic risk

Abstract Psychiatric disorders present distinct clinical challenges which are partly attributable to their multifactorial aetiology and the absence of laboratory tests that can be used to confirm diagnosis or predict risk. Psychiatric disorders are highly heritable, but also polygenic, with genetic...

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Bibliographic Details
Main Authors: A. C. Palk, S. Dalvie, J. de Vries, A. R. Martin, D. J. Stein
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Philosophy, Ethics, and Humanities in Medicine
Subjects:
Polygenic risk score
Ethics
Bioethics
Psychiatric genetic risk
Risk communication
Risk interpretation
Online Access:http://link.springer.com/article/10.1186/s13010-019-0073-8

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http://link.springer.com/article/10.1186/s13010-019-0073-8

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